Evidence for a hydrogen abstraction mechanism in P450-catalyzed N-dealkylations.

نویسندگان

  • Mehul Bhakta
  • Paul F Hollenberg
  • Kandatege Wimalasena
چکیده

The experimental evidence presented in this manuscript suggest against the widely accepted single electron/proton transfer mechanism for P450 catalyzed N-dealkylations and provides strong support for a hydrogen atom abstraction mechanism.

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عنوان ژورنال:
  • Chemical communications

دوره 2  شماره 

صفحات  -

تاریخ انتشار 2005